It was a bit early this morning and I wasn’t absolutely awake so I miscalculated my dose, 16mg with grapefruit juice, so want me luck. Thus far I discover nothing and by Wednesday most ought to have cleared my system although
Keep near the lavatory, you’ll most likely get diarrhea.
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Excellent news is that it most likely is not going to kill you. However that could be a fairly excessive dosage. Watch out!
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good factor is the actually excessive ranges solely final for round 3 days, after 3 days my ranges will probably be decrease then I had initially meant (wished to take 12, earlier highest dose 10mg with GFJ)
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If my expertise can function a information, you most likely shouldn’t fear.
I took 12 mg with grapefruit juice each 14 days for a 12 months with no unintended effects – peak was 68 ng/ml and trough was 1.9. That’s rather less than your unintentional dose, however it was long-term.
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Highest intentional dose of rapamycin ever recorded (suicide try) was slightly over 100mg and that individual survived with out challenge, so I’m not too frightened. Nonetheless it was increased than I wished to (I’m additionally an extremely quick metabolizer of rapamycin)
I’ve ever taken rapamycin 30mg + grapefruit 400ml, I skilled headache on the day 2-4, diarrhea on the day 14, zits inside the day 2-14. The Headache and the diarrhea are gentle and tolerable, however the zits could be very painful and insupportable.
