So, earlier than, at decrease doses, I used to be getting rashes/pimples on the again of my palms and on my neck. The rashes received worse once I took my weekly oral dose of Rapa + GFJ + EVOO and received higher because the week went on. As well as, I used to be utilizing the Rapa hair tonic from @Agetron every day within the morning.
I finished rubbing the hair tonic in with the hand that had the rash, and the rash went away and stayed away. If I look very fastidiously, I can nonetheless see some discoloration. I imagine it to be a bacterial-related subject, so I’m making use of an antibacterial cream to totally treatment it. Nevertheless, it seems the oral Rapamycin dose now not impacts it.
The rash on the neck remains to be getting worse after the oral dose of Rapamycin. I’m now going to check to see if not making use of the hair tonic will make it go away as nicely. Sadly, I simply upped my dosage to 4 mg + GFJ + EVOO and the rash has gotten proportionately greater and redder so it does appear associated to the quantity of Rapamycin in my system. I’m guessing my head/neck is getting a mega dose of Rapa from the hair tonic + oral complement. I ponder if extra Rapa is moving into my mind this manner? In fact I’ve no technique to inform definitively…
I additionally marvel if it might be one other ingredient of the hair tonic which is aggravating the rash on the neck though it undoubtedly appears to be Rapamycin associated because it waxes and wanes based mostly on the scale of the oral dose in addition to the timing.
Is it potential so that you can get a blood sirolimus degree take a look at the place you reside? It could be actually attention-grabbing to know what ranges you’re getting out of your mixture. Between the GFJ and EVOO you would be getting from 3 to six X or greater the conventional ranges, so equal to as much as 24mg or extra. Everyone seems to be completely different… I’ve tried as excessive as 28mg equal (with GFJ and EVOO) with no noticeable unwanted side effects, however then I additionally received a mouth sore at round 6mg as soon as, and used to get rashes each dose once I wore my Fitbit (which I’ve now stopped carrying as a result of this subject). Everyone seems to be completely different. It’s possible you’ll be discovering that this dose degree is just too excessive for you (if you happen to don’t need the aspect impact).
From what I’ve learn, rapamycin does penetrate the blood-brain barrier, and possibly the upper you go the larger the penetration (although I doubt its from the topically-applied head lotion).
Rashes are such a standard subject with rapamycin, that I think its largely the rapamycin that’s your subject.
