@medaura, my present dose is 2mg+grape-fruit (entire fruit.) My course of has been to remain at a dose till uncomfortable side effects (results I don’t like, that’s 
) go away. Solely then do I think about going up.
No, I’ve not had the next resting coronary heart price. That might concern me as effectively.
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Have you ever tried biweekly?
@L_Hayes I’m on a weekly pulse cycle. I’ve not used an each different week pulse but. My course of is gradual and regular, maintain observe of results, and re-eval each cycle. If or once I see a cause to attempt each different week, I’ll.
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Sol, did you cope with worsened fatigue on beginning? I’m taking 1mg * twice weekly with the purpose of transferring to 2mg twice weekly. I’ve me/CFS, fibro, Dysautonomia. Even at 1mg, the rapa is wiping me out terribly. I need to keep in mattress and several other instances a day I fall into a tough crash sort of sleep, day by day. This occurs even on the third day put up dose (after which it’s time to take a brand new dose).
I’ve simply taken my fourth dose. I actually don’t need to surrender but in addition curious how I’ll know if this sleep could also be serving to me heal vs an indication that rapamycin is just not proper for me.
As somebody with CFS, did you expertise this sort of crippling fatigue on startup? 
