I ran throughout an article the place Dr. Inexperienced described the enhancements that rapamycin wrought. That’s what introduced me right here. Wish to induce one thing related.
I hope to make use of this entry to trace my outcomes, quantitative and subjective.
I’ll publish some quantitative knowledge as quickly as I get check outcomes from todays go to to Labcorp. I didn’t take a ‘earlier than’ snapshot, however I’ve sufficient Kaiser historical past such that I hope I can assemble one thing helpful.
Profile
Caucasian male
age – 70y 5m
weight – 125 lbs BMI – 18
Health
Accomplished three 2000+ mile hikes at ages 59-61. Final lengthy hike in 2019, 600 miles.
May nonetheless recover from 5000 meter passes in Nepal, as of 2021.
Weekly train consists of: 2-3 150 minute walks carrying a 27 pound backpack.
As soon as every week 5 hour hike which incorporates some 30%+ grades.
3-4 20 minute classes of common stretching, sit-ups and push-ups. Very restricted weight lifting.
Bodily points
Gelatinous transformation of bone marrow – as of 2003 biopsy.
Numerous out-of-bounds blood counts, famous because the bone marrow willpower. Out of bounds, however secure.
-No signs related to the above, unintentionally uncovered once I injured a foot, and the same old blood exams had been administered.
Osteoporosis
Poor dental well being.
Osteoarthritis in arms and ft. Ache is minor, however let’s skip shaking arms.
DVTs in each legs. Taking Pradaxa.
Tinnitus
In 2016, I made a decision to strive lifting weights after not doing so for 4 years. Induced neck and shoulder pains that may’t be eradicated. Subject includes muscular tissues, not bones. I can nonetheless carry a backpack, however it’s much more painful.
Generalized aches and pains and tiredness that one often associates with getting outdated.
…that’s sufficient.
Complement routine
Pradaxa, glucosamine/chondroitin, creatine, calcium, vit D, multivitamin, omeprazole (stopped for now) melatonin for sleep, verisol collagen, hyuralonic acid.
Rapamycin Targets
Simply-noticed lower or elimination of common aches and pains.
Total feeling of larger power.
Enchancment in gum illness, famous by dentist with out prompting.
Dosage plan
Began January 6, 2023 2mg Biocon Rapacan. Further weekly doses – 3, 4, 5, 7, 10mg (at this time, Feb 10). Plan to proceed at 10mg or larger. Not including any boosters.
Advantages to date: None famous.
Uncomfortable side effects
A ridge on the within of my cheek after the primary dose. Receded after just a few days.
Pores and skin blemishes are ongoing, on scalp, face, elsewhere. Very annoying.
Some itching, appears to be decreased now, however nonetheless there.
