What am I lacking? – Rapamycin Longevity Information

Maverick why do you care? If he desires to take that a lot why do you retain arguing back-and-forth? There have been MULTIPLE research finished as much as 600 mg per week, thrice what he takes, and confirmed it was very protected…. Moreover, you had been asking him for “information“ in regards to the security of testosterone, when it has been proven at these doses to be so, all of the whereas whereas being a member of a board and your self taking a COMPLETELY experimental drug in a style that has ZERO information, and has tons of very obvious uncomfortable side effects, reminiscent of perturbed lipids, and so forth, which are instantly obvious on blood work.… I don’t know if arguing in regards to the security of a extensively prescribed drug like testosterone, all of the whereas taking rapamycin can be a nice argument to get into… I feel individuals are on this board as a result of they’re prepared to go exterior the field, so getting onto somebody for doing so in a barely totally different style simply appears extraordinarily hypocritical.

I feel it’s pointless for each of you guys to maintain arguing back-and-forth, one factor I’ve discovered as you’re not going to persuade anybody to vary their thoughts on the Web… We’re all on this board to be taught and share data, I don’t assume any of us agree utterly with all the pieces any of the opposite individuals are doing, we take what works for us and transfer on…

You don’t perceive. Maverick, like me, likes a very good old school slugfest argument. For those who don’t consider this you haven’t been following his posts.

You might be proper I don’t perceive lol… I’m all for individuals having differing opinions, I simply really feel prefer it’s getting nowhere and I can see each side. I simply don’t know why somebody going “towards the norm“ is even the slightest of huge offers on a board like this one.…

They’re arguing about what’s within the “regular vary“… Is there ANY quantity of Rapamycin, the purpose of this whole board, that’s within the “regular vary”???…Subsequently utterly moot argument

And what ageaTron is saying is appropriate, much more of the “regular vary” for the US used to finish at round 15 to 1600… I’ve blood checks from 20 years in the past and all of them ended at 1480-1600 ng/dL for testosterone higher vary… a number of articles on this have been written, some claiming it because the “Estrogenizing” of society, As the common testosterone stage of an grownup male has gone down considerably over the past 40 to 50 years…

I do see the purpose for “longevity“, there are some research that time to decrease testosterone and maybe growing older the physique much less, I completely get that. You possibly can push again and in addition say that much less testosterone additional time will result in quite a bit much less muscle/high quality of life, as of but there has not been one “over muscled” 80 to 90 12 months outdated, to cite Peter Attia…

“Usually” this wouldn’t happen. However, when you learn Agetron’s posts he has been touting ad-nauseam for fairly a while about TRT with none proof of its longevity or healthspan properties. No matter guys say, they take it for elevated libido and muscle achieve not for its well being advantages. I don’t personally care which dietary supplements individuals take. I do observe that TRT has turn into a scorching enterprise mannequin for a lot of medical doctors and clinics. For those who hearken to a sports activities radio channel it’s consistently being touted as a marvel drug for males.

Individuals, I don’t perceive this. When you’re changing a hormone, there is no such thing as a regular . The traditional vary is the low I really feel like crap vary and whenever you exchange it, it might be excessive, however the thought of changing it’s to really feel higher.

What’s the regular vary of rapamyosin in your blood? There isn’t any regular.

I used to be attempting to see if there was something I used to be lacking so far as choices to Enhance the longevity query. Generally individuals have issues which are frequent sense and even out of the field that may assist us all.

@Agetron appears joyful AF. If a testosterone stage 1500 works for him – candy! I run a trough stage of about 650 to 800, and really feel nice. Larger ranges I get agitated and grumpy.

“touting ad-nauseam for fairly a while about TRT with none proof of its longevity or healthspan properties”…… once more we’re on a board taking a drug (Rapa) that has ZERO proof in people for longevity properties. None, and actually has far more uncomfortable side effects than individuals on this board care to confess, and most cover behind the truth that we’re doing “longevity dosing“, when actually the drug is in our system, measurably, and could possibly be doing the identical adverse issues that many transplant individuals expertise, reminiscent of clots, and so forth…and I say WE, bc I’ve hope for it too… … You stated “No matter guys say, they take it (TRT) for elevated libido and muscle achieve not for its well being advantages”… I really feel like elevated libido and muscle achieve ARE well being advantages, massive time… So one thing he feels makes him have a greater life? Once more undecided I see the rationale that may be a adverse. And I really feel like elevated libido, much less physique fats, extra muscle, higher temper, higher power are all “longevity“ advantages…
I see far more “measurable” advantages of testosterone than I do rapamycin. I simply really feel like if individuals are going to gamble with rapamycin, then another person taking testosterone needs to be the least of their worries…

I imply some individuals would say that stuff you do, like Nootropics is “messing along with your mind“, “simply to be smarter”, however it doesn’t have any longevity advantages… I imply there are zero research that present Piracetam and so forth extends life in people… I’m not attempting to say you’re doing something adverse AT ALL, I too take Nootropics, piracetam, Selegiline, and so forth…I’m simply making some extent and giving an instance of how speaking about another person’s expertise after which saying it’s a adverse is maybe not an incredible technique, and ESPECIALLY on this board. Please don’t hate me for saying that in regards to the piracetam, I actually respect you as an individual, as a lot as anybody on this board and love your methods. I actually do. I feel you’re superior. Love studying all the pieces you say, you will have a really rational strategy. I feel it’s best to strive testosterone ha ha

There may be heavy proof that rapamycin extends life in all mammalian research that I do know of. We’re mammals, ergo, it’s possible that it’s going to prolong our life additionally.

In case you have a low testosterone stage or low vanity you would possibly need to take TRT to extend muscle mass and libido. The common youthful male < ~50 has ample libido and the flexibility to extend muscle mass by going to the health club.

An anecdotal remark: I’ve been going to numerous gyms for ~60 yrs and right here’s what I’ve seen. At any health club, there are a gaggle of ultra-muscular “roid” customers within the 20 –40-year-old age vary. I assume a few of them are on a TRT routine as a result of it’s authorized. Then after ~ 40, they begin to skinny out. By the point I’m taking a look at 60-plus-year-olds, they’ve largely disappeared and those which are left normally look older than their years. After 60 many of the health club goers are largely “regular” wanting individuals. The place did the “roid” customers go? I don’t know, however steroid bodybuilders normally don’t reside to a ripe outdated age. TRT doesn’t seem on any life extension protocol checklist that I’m conscious of. If it does, it must be approach down the checklist.

It’s clear you will have a adverse angle about TRT. I’m undecided that somebody who takes TRT has “low vanity”, or is a “roid consumer”, as u infer.

Your anecdotes about health club goers and scaling down after 40 don’t have anything to do with something we had been saying. I’m not speaking about “individuals within the health club”, I’m speaking about individuals on this board who’re taking TRT. Myself, I had a pituitary tumor in my mid 20s, I really feel brought on by a concussion I acquired enjoying soccer, sure concussions are sometimes listed as a trigger, and the prolactinoma that ensued brought about a lack of testosterone.…

I benchpressed 430 kilos at age 19, with none “Roids“, so I used to be in a position to construct fairly a little bit of muscle mass with out it… I acquired my first health club membership in seventh grade. What number of seventh graders are within the gyms you go to? I plan to be in a single till I die, which can or is probably not at a “ripe outdated age“, Though I’m virtually 50, and I appear to be doing fairly effectively in comparison with my friends… I’m undecided why the hostility, I used to be very respectful to you. I’ve sound arguments and also you fail to spot them or acknowledge them. TRT is in a number of, MULTIPLE lists of anti-aging/longevity routines. Guys like Ross Pelton take TRT, and say it’s a “no-brainer“ with rapamycin.

So far as rapamycin rising lifespan in mammals, and we’re mammals, thus rapamycin MUST improve human lifespan, that may be a BIG leap. You recognize that. You’ve chosen to make that leap and that’s high-quality. I’m on this board so clearly I’ve in some kind or one other. As an apart, CR ( calorie restriction) Additionally works even higher than rapamycin in mice in lots of elements. There are a number of the explanation why reducing your energy by 30% will not be an incredible technique for people although.

Yeah, CR works. It simply makes your life depressing.

Rapamycin most likely works, and it’s simple and cozy. Even pleasant for some when well being issues are eliminated.

Full of life dialog. Due to the nay sayers…I used to be just about afraid of TRT… however . Once I examined and met with my doctor 4 years in the past and began my prescription, I noticed that it was an incredible profit in my well being… and for my growing older points.

Simply talking out so others might take into account it… going natty at 60 and older not all the time nice.

Right here is one thing that may assist… for these wanting. Do TRT… or don’t. However as you age… males lose testosterone get weak and sick… for girl it’s estrogen… there are alternatives to assist. That’s it.

“CR works… it simply makes your life depressing”
Yeah DeStrider that’s what I’m saying… not sustainable for a human, because of psychological misery! Suicide doesn’t assist longevity!!

And DesertShores, I do agree that there’s a bunch of douchebags in gyms that give testosterone a foul identify….and I do know in my image I appear like a type of douchebags lol… It’s from Google that I connected to this account from three years in the past ha ha… I attempted to eliminate it after I’d already signed up and it doesn’t seem there may be a straightforward strategy to do it…

Sure, I feel the principle factor about this board that I’d wish to proceed is the “Decide not” stance, which is the angle of many of the members.
We’re all threat takers and taking some gambles, hopefully, knowledgeable by science. I’ve not seen a dumb individual on this discussion board.
I used to be nonetheless a really sturdy, tall athlete at age 59 after I selected to get testosterone substitute two years in the past, and I did it as a result of I might see the lengthy, gradual, muscular decline approaching. Regardless of how a lot health club work I put in, it was like standing nonetheless. Including Testosterone has been very useful. My numbers are just like agetron.
However please, don’t be “that man” that speaks with absolute certainty as a result of you will have by no means lived my life, confronted the issues I’ve confronted, and you already know what’s greatest for you, and that’s it.
Each time we seek advice from ourselves and the advantages we consider have occurred, it’s all the time an N of 1. So I don’t assume we now have to maintain saying this on a regular basis.

Good to have a doctor chimming in and including one other voice of purpose in affected person selection – want.

TRT will not be for everybody – however needs to be a consideration amongst different issues when one hits their 50’s and up. Your testosterone goes to be diminished and you will really feel these impacts. In case you are in search of high quality of life, well being and life span – it’s price consideration. Residing the longest with out the pleasure of your physique’s operate, psychological/thoughts and bodily exercise – in my opnion isn’t residing.

I’m relying on rapamycin and TRT offering me with all of the above.

Straw males left and proper right here. I’m not towards TRT and I’m not towards private selection.

I’m towards advocating for a dose that’s thrice greater than the median.

You can not examine outcomes between labs, his values are nonetheless inside reference for his lab and even when they had been barely out of refence, not all barely irregular lab values are problematic (only some are)