Does rapamycin make your face look youthful?

Does rapamycin make your face look youthful? Thanks.

I’ve been utilizing it for a lot too little time to note any distinction. There are some research for topical rapamyicn that reveals some promise.

e.g.

Simply this morning i discovered additionally this web page

however each are for topical cream. Wouldn’t find out about systemic use. May need some impact as nicely.

Thanks. However once you say you’ve been taking it for a lot too little time … how lengthy have you ever been taking it? Thanks

I ponder the identical. I’ve solely been on rapamycin for two months however within the final couple of weeks I’ve had 4 folks assume I used to be in my 40’s. I’ve not had anybody assume I used to be youthful than my age for a loooooong time in order that’s promising. It could simply be a coincidence in fact.

As talked about, there’s proof to recommend that topical rapamycin will help pores and skin well being.

There may be a variety of proof that rapamycin will gradual the getting older on lots of the physique’s organs… see this thread: Can Rapamycin restore your organs and due to this fact reverse getting older?

The pores and skin is the biggest organ of the physique, and moreover there’s important muscle and different tissue within the face. I strongly suspect, however can’t but show, that rapamycin will considerably gradual (however maybe not reverse) many age-related adjustments to the face.

If what is occurring within the many different organs of the physique, can also be taking place within the pores and skin and muscle tissues of the face, then we must always see a lot much less sagging of pores and skin and tissue, and muscle atrophy, that’s usually seen in folks as they get age.

I’ve contacted rapamycin researchers about this, as there are presently long-term research ongoing with monkeys utilizing excessive dosing of rapamycin. It wouldn’t be very exhausting to do pores and skin samples and photograph evalutation of the handled monkeys vs. the management monkeys, to guage this difficulty. We’ll see if we are able to get it transferring ahead and I’ll let you recognize.

Second dose. I’ll report again in time…

Sure I agree that there could be a risk that it could make pores and skin youthful, particularly by eradicating solar harm through autophagy I suppose. Possibly immune activation would stimulate collagen manufacturing by fibroblasts.

i’ve been on rapamycin roughly two years and utilizing a topical rapamycin face cream for 4 months. it’s exhausting to know if I look youthful however it positively feels youthful (purely anecdotal).

I’m truly cautious of attempting rapamycin in case it does stimulate collagen, as a result of I had a remedy which stimulated an excessive amount of collagen in my jaw and I would like it to go down!