Are there papers on this? My expertise with rapamycin has been… dangerous. I’ve been trying to find data that may recommend that some individuals are hypersensitive however haven’t discovered a lot.
Primarily based on my expertise I can’t think about taking greater than 1mg per week, and but most individuals take at the very least 5 occasions that.
I received my sirolimus from an enormous US pharmacy, however I’m going to go searching right here for a tablet identification thread.
Not that I can inform.
I havent managed the variables, so the confounding affect of afternoon espresso, late dinner, numerous dietary supplements, makes any results laborious to find out.
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I don’t assume there’s any analysis re cons and execs of particular person dosing but. We’re nonetheless at a really early stage of utilizing Rapa. I’m very delicate to drugs generally, together with Rapa, and often want a a lot smaller dose than many individuals do. After making an attempt totally different protocols, I got here to a conclusion that it’s essential for me to maintain not lower than 12 days, however ideally extra, between doses. If I do this, I don’t have damaging unintended effects. My major purpose is to help my transplanted kidney, so my expertise could not work for many who take Rapa just for longevity.
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I’m curious why you say that your sleep high quality isn’t what it must be. I imagine they offer you a little bit crown at a rating of 85. My query is whether or not Oura gives a legitimate sleep evaluation. I’ve been utilizing the ring for almost a 12 months now. I additionally bought a
Match bit concurrently the Oura ring. What I do know for certain is that information from the Oura and the Fitbit aren’t considerably associated. I’ve graphs of the info for sleep high quality, sleep time, deep sleep time, hrv, energy burned, and so forth. Aside from sleep time, the R^2 correlation for all these are lower than .05. Sleep time correlates higher at about .65. Has anybody else carried out an identical evaluation. I do know that many occasions the sleep rating from Oura doesn’t mesh with how I really feel.
Here’s a typical comparability of sleep scores for Oura and Fitbit (recorded for a similar night time).
Fascinating information… What we want is a comparability to polysomnography.
My bias, as an proprietor, is that Oura is extra correct that Fitbit. Actually Matthew Walker wears one…
