Are there papers on this? My expertise with rapamycin has been… unhealthy. I’ve been looking for data that may counsel that some individuals are hypersensitive however haven’t discovered a lot.
Primarily based on my expertise I can’t think about taking greater than 1mg per week, and but most individuals take not less than 5 occasions that.
I bought my sirolimus from an enormous US pharmacy, however I’m going to go searching right here for a capsule identification thread.
Not that I can inform.
I havent managed the variables, so the confounding affect of afternoon espresso, late dinner, varied dietary supplements, makes any results arduous to find out.
1 Like
I don’t assume there’s any analysis re cons and execs of particular person dosing but. We’re nonetheless at a really early stage of utilizing Rapa. I’m very delicate to drugs on the whole, together with Rapa, and often want a a lot smaller dose than many individuals do. After attempting completely different protocols, I got here to a conclusion that it’s vital for me to maintain not lower than 12 days, however ideally extra, between doses. If I do this, I don’t have unfavourable unwanted effects. My major aim is to help my transplanted kidney, so my expertise could not work for individuals who take Rapa just for longevity.
3 Likes
I’m curious why you say that your sleep high quality isn’t what it ought to be. I consider they provide you somewhat crown at a rating of 85. My query is whether or not Oura gives a legitimate sleep evaluation. I’ve been utilizing the ring for almost a yr now. I additionally bought a
Match bit concurrently the Oura ring. What I do know for positive is that knowledge from the Oura and the Fitbit should not considerably associated. I’ve graphs of the information for sleep high quality, sleep time, deep sleep time, hrv, energy burned, and so on. Aside from sleep time, the R^2 correlation for all these are lower than .05. Sleep time correlates higher at about .65. Has anybody else performed the same evaluation. I do know that many occasions the sleep rating from Oura doesn’t mesh with how I really feel.
Here’s a typical comparability of sleep scores for Oura and Fitbit (recorded for a similar night time).
Fascinating knowledge… What we’d like is a comparability to polysomnography.
My bias, as an proprietor, is that Oura is extra correct that Fitbit. Definitely Matthew Walker wears one…
I discovered from the Oura evaluation that I used to be getting very low REM and Deep sleep, so I began experimenting with completely different dietary supplements and completely different night patterns.
After a whole lot of trial and error, my REM and Deep are actually each repeatedly scoring at acceptable quantities. I really feel higher and extra energetic throughout the day and can proceed to experiment with variations. I havent paid a lot consideration but to the opposite sleep scores.
For monitoring train I wouldnt suggest Oura. At this level my concern has been with sleep high quality
Might you pls share what dietary supplements you’re taking for higher sleep rating?
