jueves, octubre 15, 2026
InicioAnti AgingDifferent 40 yr Olds and About to Take the Plunge? - rapamycin

Different 40 yr Olds and About to Take the Plunge? – rapamycin


First time posting, been hesitant to chime in on something. I’ve sufficient in widespread with you that I figured it was time. My spouse and I began rapamycin 2 months in the past. We met in school as runners and have by no means stopped.
She’s late 30s, I’m early 40s and we stay very lively existence. Nonetheless operating 40+ miles every week and if we’re coaching for a marathon we ramp again up over 60 miles every week. I’m positive you may relate!

We’ve ramped up slowly from 1mg. My spouse is at 3mg and I’m at 4mg after 2 months of a gradual ramp. We seen little issues virtually straight away. I’d say the very first thing we seen is that any exercises/runs we did the identical day as taking rapamycin, we’re fairly brutal (we raise or run 6 days every week). We have been additionally much more sore after these exercises and even appeared to get well slower.
After 2 months now, the soreness is generally gone. We’re hoping which means we’ve had optimistic variations the place our our bodies have gotten a bit extra use to the drug.
We’re doing a little self experimentation, watching blood work, and incorporating the rapamycin instantly with our coaching plans; approaching taking it as if it’s a part of our coaching program.
We all know our our bodies fairly effectively, so we will largely inform variations due to one thing new we’ve launched into our existence. I feel we’ve each seen a loss in visceral fats, myself not as a lot as my spouse. My spouse has at all times struggled balancing her hormones with coaching, which might trigger weight acquire regardless of the quantity she workout routines. This has particularly been the case prior to now when she ramps up her cardio train.
After two weeks she noticed noticeable variations in her physique response to exercises. Whereas she’s been extra sore after her exhausting days, she’s additionally not had the unwanted effects she’s had prior to now whereas doing cardio coaching (n = 1). She’s ramped up her mileage and is operating fairly effectively and feels nice!

Oh, I’ve additionally traditionally struggled with insomnia. The primary couple nights after my weekly dose I sleep like a rock, that’s been fantastic!




5 Likes

Wow, thanks for the reply! I discovered it tremendous helpful. Whereas I’m now not an lively runner, I’m eager to get again into it even when it’s only for some further cardio. And the seaside is just 2 miles from my home now so…

I didn’t count on you have been going to say the rapamycin days made for tougher exercises. That’s fascinating and the alternative of what I might have guessed.

The visceral fats and sleep stuff can be tremendous fascinating. I’ll keep watch over each. I’ve battled with sleep for so long as I can keep in mind. I’ve tried all the things from melatonin to magnesium, and so on. however I bought an EightSleep mattress and “pod” (or no matter they name it) and that’s helped greater than something.

My rapamycin is seemingly almost right here so I have to get cracking on my blood work. I didn’t count on it to reach so quick!



1 Like

37 M, lively (weights/cardio). Simply took first dose ever of 2mg rapa at the moment. Then I handed out for two hours for a noon nap, which is very uncommon for me. I really feel like at the moment’s exercise may be a slog.

Plan to ramp up slowly to about 4-6mg and keep there for some time.

I don’t understand how another folks report discovering these things stimulating, feels fairly sedating to me.



2 Likes

Wow, fascinating! Sure, all the things I see appears to be of us saying they really feel puffed up on “dosing day”.

Did you do blood work earlier than beginning? Mine is arriving any day now and I do know it’s going to be exhausting for me to go do blood work earlier than beginning at this level.



2 Likes

I’m in the identical boat… however I couldn’t wait. Having bloodwork executed within the subsequent week or so. I don’t suppose a single 2 mg rapa dose ought to affect it an excessive amount of. I’ll hold doing bloodwork as soon as each 6 weeks or so to keep watch over it, extra involved in regards to the long-term developments. Though to be frank, not that involved about rapamycin on the whole, it appears awfully secure.



1 Like

Agreed. I’m not likely involved in regards to the security. I’m extra considering a “earlier than/after” kind of comparability so I can quantify what affect it’s having. We’ll see if I can maintain off lol



2 Likes

Alright you guys most likely don’t want a play by play of my first dose however feeling actually good and energetic now. Nap —> numerous vitality. Trying ahead to taking this hopefully indefinitely.



2 Likes

Hey man, I don’t thoughts the play-by-play! lol

That’s good to listen to. I plan to take mine within the mornings (I’m often up round 5am) so hoping to actually really feel that vitality enhance every week… most likely on Mondays.

RELATED ARTICLES

DEJA UNA RESPUESTA

Por favor ingrese su comentario!
Por favor ingrese su nombre aquí

Most Popular

Recent Comments

Esta web utiliza cookies propias para su correcto funcionamiento. Al hacer clic en el botón Aceptar, acepta el uso de estas tecnologías y el procesamiento de tus datos para estos propósitos. Más información
Privacidad