, it’s of curiosity to know whether or not addition of a small dose of acarbose to quickly digestible starch can change the digestive profile to that of a slowly digestible starch. If that is achieved, one would anticipate with acarbose a decrease inflow charge of starch-derived glucose within the early postprandial interval and a better inflow charge within the late postprandial interval, leading to roughly the identical bioavailability of glucose as with out acarbose. Nevertheless, in our research we discovered {that a} low dose of
12.5 mg of acarbose added to quickly digestible corn pasta considerably decreased the speed of look of exogenous glucose within the first 4 h after ingestion, whereas within the postprandial interval between 4 and 6 h the RaEx was the identical. Consequently, the bioavailability of starch through the 6-h check interval was decreased by 22%. As well as, the share of the ingested dose that was excreted as 13CO2 through the research interval was considerably decreased by acarbose (CP 37.5 ± 2.8 %dose; CPac 27.2 ± 2.2 %dose; P = 0.004). Related knowledge have been discovered by Achour et al. [21] evaluating digestible and partially indigestible cornstarch: the share of the ingested dose excreted after ingestion of digestible starch was 35.3 ± 3.0 and that after partially indigestible starch 28.2 ± 1.8 over a interval of 8 h.
