My glucose was at all times regular. Now, with metformin + Sirolimus it’s low-normal.
It’s my insulin degree that appears to be the issue. Once I had it checked earlier than I began Sirolimus it was 2. Notice that that was not a fasting studying; it was about 2 hours after a big breakfast.
I believe some individuals may be complicated glucose ranges and insulin ranges. They’re clearly utterly completely different (though linked in some methods).
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Sadly, I get a bizarre response to Metformin. Itchy pores and skin, complications, edema, and this very odd factor – veins begin bulging (not kidding). My kidney and liver operate appear high quality in line with my bloodwork so I don’t know what it occurring, allergic I suppose.
So that is attention-grabbing. My PCP had an endocrinologist evaluation my check outcomes, he was conscious I’m on Rapamycin as it’s in my file. Listed here are his feedback on my low insulin.
“He’s euglycemic with regular A1c. His insulin ranges, achieved I assume as a result of that they had been achieved within the exterior research as a part of a protocol, are undetectable within the fasting state, which isn’t shocking given that he’s not overweight (which might trigger insulin resistance, and would possibly end in a better fasting and particularly publish prandial insulin degree).
At any charge, there isn’t any medical significance to the insulin degree. This may not be a part of any testing that we might usually do for a affected person like this until hypoglycemia had been suspected and documented. You may reassure him that there isn’t any significance to this, and I might advise that you simply not proceed to check insulin ranges.”
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Properly, I discover that shocking.
My physician virtually fell off his chair when he noticed my insulin degree…and proceeded to interrogate me to attempt to discover out why it was so low.
