What about bulk pomegranate powder that some firms promote. I’m questioning if that will work. We additionally must discover a check to see if we’ve the correct intestine micro organism.
Hello Agetron, is that with GFJ?
So are you aiming 6mg rap + GFJ … So about 18-21mg equal?
Thanks
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Hi there L_Hayes –
I used to be doing 6mg with one contemporary squeezed Crimson Grapefruit juice to drink with the capsules and I used to be getting about 36 ng/mL for 7 months. My biolgical age went from low to larger (37 years to 51 years – misplaced 15 years) with GlycanAge and TruMe. Not good. So, I’ve lowered my dose 1/3 because the final time I dosed.
Now I’m doing 2mg with GFJ and getting about 12 ng.mL with 10 days between dosing. My weight is already choosing up just a few kilos (not a foul factor as I used to be fairly shredded – no fats). Possibly too skinny.
I’m not satisfied that the upper dose (38 ng/mL) for 7 months was higher for me. I’m going to go together with a few complete 12 mg dose and retest in 6 months and see if my organic age improves – i.e. goes again down.
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I’m nonetheless struggling to grasp why lots of my epigenetic markers obtained worse after taking rapamycin for over a yr.
Earlier than taking rapamycin my epigenetic age on the Levine and the Growing old.Ai checks my phenotypic age on the Levine check was 63 yrs outdated. After 1+ yr on rapamycin, my phenotypic age is 73 yrs outdated. I’m ~82 years outdated.
My major longevity routine for many years, train and supplementation:
Train
Time-restricted feeding (TRF)
Low carb weight loss plan
Metformin
Melatonin
Lithium
Numerous different dietary supplements intermittently
FWIW: New article on TRF identified on Twitter by
Professor at Salk Institute, Satchin Panda
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That could be glucose. I feel you gave the small print earlier than. Each methods are very aware of glucose.
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As I beforehand posted my glucose ranges didn’t change in any vital approach.
The most important modifications have been MCV and RDW.
Growing old.AI and Levine are each formulaic calculators, so if you’ll find out which biomarker moved essentially the most, you may then fiddle with it.
Right here’s what I might do in the event you actually need to know.
- Enter your outdated numbers into the calculator of your selection.
- Replace one variable at a time along with your new values after which see the way it modifications your ‘age’
This can let you know the offender(s) for the rise in age. It shouldn’t even take you that lengthy both.
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Your first line seems like RDW and the second isnt Rdw
Sorry, completely screwed that up!
Listed here are the actuall charts:
If MCV modifications RDW will go up while it’s altering. MCV issues might be a B12 scarcity or copper depletion.
MCV will also be harmed (elevated) by heavy alcohol consumption notably alcohol consumption with out copper supplementation.
It’s doable that Rapamycin will increase the requirement for B12. I might not be shocked if that have been to be the case.
Do you discover that your palms (or different components of your physique) tingle? In that case that’s fairly more likely to be a scarcity of B12 (peripheral neuropathy).
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I’m new to longevity targets (so I do know little or no) however my well being stack been has been the next for fairly a while:
NDT
Bio similar HRT
Melatonin
Lactoferrin
Multi vitamin/mineral & b-complex
K2 MK4
Methylene blue
Crimson gentle
True Darkish blue blockers
Black out curtains
Keto weight loss plan
Sprints
Weighted vest
I might change to MK7. MK4 has a really brief half life.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502319/
Mk4 and mk7 do various things. I take each.
