Aspect Results of Rapamycin (half 2)

I watched the video. It’s the identical argument towards spermidine – It could possibly’t be discovered within the blood after dosing. That is why the ITP had issues with it. Dr. Brad is simply regurgitating that data.

Different research have proven it to assist autophagy.

I take advantage of it as an autophagy booster and blend it into the EVOO after I take my Rapa. If it boosts autophagy, I would like it to work synergistically with Rapamycin. Worst case I’m losing cash. Greatest case I’m bettering my results of Rapamycin. I don’t see any well being draw back to taking a excessive dose of spermidine (wheat germ). It’s a moonshot although.

I take Rapamycin on Saturday morning and I take spermidine Saturday, Sunday, Monday and Tuesday.

Right here is an replace on my suspected case of bacterial oral an infection as a facet impact of biweekly excessive dose rapamycin. As a precaution I just lately modified from biweekly to triweekly dosing.

Referred for potential root canal, I consulted a high endodontist within the Washington DC space. Nonetheless, from his examination he reported a standard pulp and was unable to find out from his checks and a full mouth scan why one tooth was delicate and why there was irritation. It was not the same old suspects.

He known as me at house on the finish of the day to inform me he was in a position to see that I presumably had a cemental tear, i.e. a thread of cementum separated from the basis. He mentioned it had most likely been 7 years because the final time he noticed one.

So the irritation and erosion of bone was presumably from the tear moderately than from micro organism.

Earlier than continuing to the periodontist for a closing opinion and oral surgical procedure I’ll attempt for a couple of months to regenerate the bone and heal the cementum. Since there isn’t a urgency, I believe its price a attempt to induce extra bone formation with 50mg Zinc, vitamin K2, and rapamycin toothpaste plus water pik utilizing rapamycin mouthwash with a purpose to attain deep into the pocket.

Sucking melatonin at time for the circadian cycle can scale back oral irritation. An excellent time is in the course of the early morning earlier than lastly waking.

Good concept. I can attempt that earlier than my closing awakening. If I’m awake sufficient to recollect.

It has the benefit of topping up your mitochondrial melatonin all through the physique and likewise lowering oral irritation. I take advantage of the biovea, eurovital kind which has a fairly good berry flavour. Nonetheless, if you’re within the USA there could also be different ones.

As I reported on my journey log, within the late afternoon after taking my first 1mg dose of rapa within the morning I acquired two enormous herpes rashes round my nostril and inside my nostrils. After that some complications appeared, and I by no means have complications. Over evening I acquired some soreness in my throat and now I really feel like a chilly is coming.

Coincidence or not, I dont know… will see.

Did they fight duraphat, previous stuff however works rather well

Sadly, the rashes I had earlier than have returned in the identical location and are getting bigger. Is it potential they’re bacterial infections? They get dramatically lighter after I cease Rapamycin however they’re nonetheless there. Any ideas for eliminating these annoyances?

Identical right here, it appears like not a bacterial an infection, as a result of I took varied oral antibiotics, and it didn’t assist.

Appears to be like like we’re in the identical boat, Lee. For those who discover something that works, put up it right here. I’ve tried an antibacterial ointment, hydrocortisone cream and adapalene tonight. Right here’s hoping the combo works.

On this case report, benzoyl peroxide, erythromycin, adapalene, doxycycline are all ineffective for the rapamycin zits.

Topical remedy with benzoyl peroxide, erythromycin, after which
adapalene adopted by oral remedy with
doxycycline (2 ! 50 mg/day) was ineffective.

Nonetheless on this paper, isoconazole efficiently handled the zits in 3 of 6 sufferers.

One affected person handled his eruption with isoconazole spontaneously.
As a result of this remedy was thought-about very efficient, 6 different sufferers had been handled with isoconazole,
efficiently in 3 of them

Resulting from that paper, just lately I attempted isoconazole on my zits, it didn’t work, however I’ve a excellent news! After I utilized isoconazole cream within the very early stage of zits, it was utterly healed.

In case you are about to have an zits, apply isoconazole ASAP, you could have probability to treatment it. Isoconazole is reasonable in Taiwan right here, you possibly can simply get it from pharmacy, however Isoconazole has its restrict, it’s very ineffective for the mature zits, I’m nonetheless in search of for a simpler option to deal with rapamycin zits.

Good to know. I’ll attempt that. I want they’d go away rapidly.

Thanks for that info. It definitely appears price attempting if I can get it.

I ramped as much as 6-8 mg weekly with none actual negative effects. Tried 4 mg with the juice of a recent grapefruit just lately and some days later I’ve acquired a runny nostril.

DeStrider, I’m undoubtedly not an professional, however it appears to me that adapalene, although milder than Retin-A, may trigger some pores and skin irritation and presumably sufficient to worsen the rapamycin rash. My expertise with rapamycin rash is that some merchandise had no impact, others (perhaps adapalene?) exacerbated the rash, and just one product (hydrocortison cream) gave non permanent aid. After all, that is simply my expertise, and everyone seems to be totally different.