Different 40 yr Olds and About to Take the Plunge? – rapamycin

Nice evaluation. I assume we’re pioneers right here. Hopefully we’re on the best aspect of historical past lol

Wow, fascinating relating to your epigenetic age being increased. I take into account myself in good well being however have by no means had my blood performed to essentially know for positive. So whereas I’d assume my epigenetic age is decrease than my chronological age, I assume I actually don’t have a clue.

I’m beginning to assume I’ll see/really feel little or no profit however hoping I can see the distinction in my blood exams to realize it’s working underneath the floor.

Early 40s right here, been doing this for about 5 months now. I really like rapa day every week as a result of I really feel higher on that day than every other, a number of power, bodily and psychological. Might be doing my first bloodwork since beginning subsequent week so I’m very curious to see if there are any modifications. Total I’m tremendous joyful to get a bit burst of power and know that I’m hopefully stopping unhealthy issues down the road.

I’m 48 and simply began taking Rapamycin. I’m near speaking to household, however I figured I’d work as much as a stable dose over a month or two and see how my physique reacts. In spite of everything, my household share a great quantity of my genetic make-up.

Once I inform them I believe I’ll share some movies and blogs from elsewhere on this web site. Plus give this web site.

Once you get your blood examined, if you wish to use the Levine Phenotypal Age calculator test this submit A Pleasant, Organic Age Discount Competitors? – #60 by HigoMe33

It’s enjoyable {that a} group of us are all in our 40’s and starting now. Let’s get collectively in 60 years and have a celebration!

Nicely, I took a spit epigenetic take a look at and it says my epigenetic age is 59. I took a blood pattern evaluation at Growing older.ai and it says my age is 28. In case you common the 2 collectively, you get my actual age. So, it simply goes to indicate you that age testing remains to be fairly variable.

Similar right here I’m 48 and would’ve have began earlier If I’d have had entry to Rapa. I’ve been a long life nerd for years and thought it was out of attain till I stumbled upon this web site. I’m very grateful to have discovered it. I do suppose that it’s extremely early although. I personally don’t really feel comfy attempting to steer my household to get on it. Whereas I’m really feel pretty assured that we’ll discover out conclusively Rapa does prolong lifespan within the close to future there are dangers and uncertainty concerned. I get the impression that we’re within the minority. Not everybody is ready to take unproven medication and never everybody ought to.

G’day Tbiz

I’m 43 and have been taking Rapa for simply over two months now. I adopted RapAdmins recommendation and ramped up slowly (1mg every week, now at 6mg). I’ve not skilled any constructive or adverse uncomfortable side effects to this point, other than psychological (feeling constructive in regards to the future).
I’m fairly match, lean, eat wholesome and take another dietary supplements / drugs like most others on the location.

Cheers

Olive oil. I might advise towards GFJ

Seems like we’re in comparable boats relating to health. I would like to essentially dial down any expectations and simply hope to see modifications in blood work to realize it’s having a constructive influence. Thanks!

I’ve been taking rapamycin for a 12 months and have seen no constructive results on any of my blood work, solely adverse results. Actually, I needed to decrease my dosages to get my blood markers again to regular. My markers are nonetheless inferior to they had been earlier than I began rapamycin.
My private constructive results of rapamycin are associated to its constructive results on my pores and skin and significantly improved sleep high quality. I’m previous and previous folks typically have sleep issues like getting 8 hrs of fine sleep at night time. I’m now sleeping like I did after I was a young person.
The anti-cancer results of rapamycin have diminished the variety of actinic keratoses that I’ve to primarily zero. Attributable to extreme solar publicity to the solar after I was younger I developed persistent actinic keratosis, which precipitated me to hunt remedies a minimum of twice a 12 months for many years. I haven’t needed to see my dermatologist for over a 12 months now and don’t plan to see him anytime quickly.

Backside line: Whereas rapamycin has confirmed life-extension results in mammals, don’t be shocked in case your blood work doesn’t look higher after beginning rapamycin. This was a shocking outcome for me and has not been correctly defined.

Wow, fascinating mixture of outcomes! I haven’t heard anybody speak about their blood work being worse off since beginning rapamycin. Good to know!

Plainly the positives are outweighing the negatives for you? It sounds such as you aren’t planning to cease the rapamycin?

TVBiz, Take note of that knee ache. I’m fairly a bit older than you and have slowly moved away from jogging to actions that don’t appear to put on my joints as quick as I believe jogging did. I nonetheless stroll and hike, however have integrated swimming and stationary biking to scale back joint stress. Unusual as it might appear doing a whole lot of squats in units as soon as every week doesn’t appear to trigger joint ache. Collagen peptides could also be useful, however I actually haven’t seen any enchancment with that complement. And, rapamycin to enhance the joints? Nicely, I’m not relying on rapamycin for assist in that space. However, it’s completely unknown at this level. Oh, and yet one more factor about joint ache, in case your are obese, losing a few pounds can cut back put on and tear on the joints and presumably cut back ache.

Sure, despite questionable blood work outcomes, I’m nonetheless a believer in rapamycin and plan on taking it for the remainder of my life. BTW, I used to be in glorious form and my blood work was additionally excellent earlier than I began rapamycin. My epigenetic age was youthful utilizing the Levine calculator earlier than I began taking rapamycin. Since I didn’t have any concept that rapamycin would have an effect on my actinic keratoses or sleep, I really feel that they weren’t placebo results.

Beginning on rapamycin as quickly as my order will get by way of customs. I’m 45 and have an epigenetic age of 38. I’m in good condition, so I’m not anticipating life-changing outcomes.

I discussed it to my spouse, however I don’t plan on telling anybody else. I actually couldn’t care much less about anybody else’s opinion about it, anyway.

I’ve a 15 yr previous, a 4 yr previous, a 3 yr previous and a 3 month previous . . . I wish to keep robust and youthful for them (and myself) so long as attainable.

Plan on beginning at 1mg per week and shifting up slowly. I actually respect all the expertise sharing you guys present on this discussion board!

Sure, Jay, the knee ache was an enormous pink flag for me. I took discover! Initially I believed I may strengthen it however I believe I used to be overdoing it. I’ve moved towards “babying” it now and it appears to be enhancing. I nonetheless consider attempting to strengthen it might assist… we’ll see. I’m not obese, in order that’s not it. I’m fairly slim at simply over 150 pound and 6’0″.

Superior, Phil. I think about you’re excited to get happening it like I’m! I even have kiddos… a 4 and 6 y/o (each boys).

So, I’m 82 years previous and undoubtably have some arthritis in all of my joints. However, I’m just about ache free. The one factor that bothered me was my proper knee which I tweaked a few years in the past taking part in tennis. I had ache in my proper knee for many years. A few years in the past I began taking boswellia serrata, which helped alot, however didn’t fully remove the issue. Then I began seeing just a few articles on strolling backward for the reduction of knee ache.
It was remarkably efficient. I discovered reduction after my first time strolling backwards on a treadmill on the fitness center. I nonetheless can’t consider how efficient it was for me. It actually doesn’t take loads of strolling backwards to search out reduction of knee ache. Now if my knee begins bothering me I simply begin the strolling backwards train for some time. You don’t want a treadmill, simply do strolling backwards for some time.

“The 6-week retro strolling program in contrast with ahead strolling or management teams resulted in larger discount in ache and useful incapacity and improved quadriceps muscle power and efficiency in people with knee OA.”

“Strolling backwards on a treadmill — additionally known as retro strolling — is a bit trick bodily therapists advocate as a manner to enhance knee ache.”
“Strolling Backwards On A Treadmill Is A Godsend For Knee Ache”

Reverse Strolling on the Treadmill for Bodily Remedy.

I really like the concept of strolling backwards on a treadmill. I’ve by no means tried however will. I’ve been sporadically working backwards uphill since my teenagers, when an uncle urged it, impressed by Mohammed Ali. Brilliannt for constructing vmo’s (vastus medialis obliques)

Thanks for this. I’ll give strolling backwards a strive. Sounds so easy!