Dr. Inexperienced truly recommends 3 MG quite than 45 MG. He makes use of the next % due to solar harm to his scalp. He prescribed me eight drugs (24 MG) to make use of over the subsequent 12-18 months to make my very own do it your self pores and skin cream. So far as OneSkin to rapamycin, I examined each, one on every arm. OneSkin was fingers down the winner in my n=1 experiment. Now I take advantage of each.
I nonetheless haven’t seen any significant purpose so as to add a cream like Olay to the rapamycin plus Transcutol+water combination. It simply looks as if a waste of some rapamycin to me.
Placed on the Olay afterward should you suppose you want a cream. I’m discovering that the straight rapamycin+Transcutol+ water is working nice and I’m seeing a reversal of age spots on my fingers.
Most of those beauty lotions usually are not efficient, however they’ve put a number of effort into absorption. None of my rapamycin is wasted aside from maybe a tiny, tiny bit on the backside of the jar.
I feel the rationale is easy – many individuals already use a physique/facial pores and skin moisturizer each day, so quite than add complexity to individuals’s every day routine the researchers simply added it to one thing individuals may use every day already. So – minimizing individuals’s want for habits change (which is at all times a superb factor if you’d like individuals to undertake one thing new).
Plus, many of those moisturizers have compounds which might be good for the pores and skin – e.g. CereVe with Cerimides, and so on. , so the addition of rapamycin makes a superb product, even higher, and also you don’t want to vary your every day habits.
I discover it much less problematic than not figuring out how a lot of my rapamycin has been dissolved. For all, I do know any provider corresponding to Transcutol is already saturated within the cream and doesn’t dissolve any rapamycin in any respect. For these dissolving the rapamycin in some Transcutol or DMSO earlier than including it to the cream, it’s a totally different story. Spritzing on slightly Transcutol, rapamycin, and water resolution earlier than placing on the lotion is hardly a chore.
However, when you add rapamycin to any one of many myriads of lotions in the marketplace you don’t have any concept what quantity might be out there for absorption or how a lot might be absorbed.
Simply my opinion after all however I’ll select what I think about to be the extra dependable resolution. (No pun supposed)
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How a lot rapamycin are you crushing up, and into what amount of liquid/cream are you mixing it? The mixtures are given in % of rapamycin, so a 0.045% resolution just isn’t essentially 45 mg of rapamycin in a given amount of liquid. Figuring out the quantity of rapamycin and amount of liquid will let me calculate the % for comparability.
I’ve used about three of the 50 ml OneSkin OS-01 on my face over the previous 6 months most likely. Whereas I do just like the outcomes usually, I really feel it’s approach overpriced. They counsel utilizing it twice a day, and with that quantity I might simply see going via two 50 ml tubes of it per 30 days. At $100-120 per 30 days it provides up. I’d be extra apt to purchase if it have been about $80 for 150 ml. It’s unclear if their Physique lotion has an identical quantity of the peptide. If we are able to get related outcomes with rapamycin pores and skin cream I’d be blissful.
Have you ever been utilizing the Face or Physique cream, and have you ever in contrast the 2?
Please go to the highest of the thread. I imagine your entire questions are answered within the matter.
So… what has all of your experiences with rapamycin cream been like, now that you’ve used it for some time?
Do you get phases of dry pores and skin, like with tretinoin? Other than this, how else would you evaluate it with tretinoin?
