DIY Rapamycin pores and skin cream – Rapamycin Longevity Information

I nonetheless haven’t seen any significant purpose so as to add a cream like Olay to the rapamycin plus Transcutol+water combination. It simply looks as if a waste of some rapamycin to me.
Placed on the Olay afterward if you happen to suppose you want a cream. I’m discovering that the straight rapamycin+Transcutol+ water is working nice and I’m seeing a reversal of age spots on my palms.

Most of those beauty lotions usually are not efficient, however they’ve put quite a lot of effort into absorption. None of my rapamycin is wasted aside from maybe a tiny, tiny bit on the backside of the jar.

I believe the rationale is easy – many individuals already use a physique/facial pores and skin moisturizer each day, so somewhat than add complexity to individuals’s every day routine the researchers simply added it to one thing individuals may use every day already. So – minimizing individuals’s want for conduct change (which is at all times factor in order for you individuals to undertake one thing new).

Plus, many of those moisturizers have compounds which are good for the pores and skin – e.g. CereVe with Cerimides, and so on. , so the addition of rapamycin makes product, even higher, and also you don’t want to alter your every day habits.

I discover it much less problematic than not realizing how a lot of my rapamycin has been dissolved. For all, I do know any service akin to Transcutol is already saturated within the cream and doesn’t dissolve any rapamycin in any respect. For these dissolving the rapamycin in some Transcutol or DMSO earlier than including it to the cream, it’s a completely different story. Spritzing on slightly Transcutol, rapamycin, and water resolution earlier than placing on the lotion is hardly a chore.
However, when you add rapamycin to any one of many myriads of lotions in the marketplace you don’t have any concept what quantity will likely be obtainable for absorption or how a lot will likely be absorbed.
Simply my opinion after all however I’ll select what I think about to be the extra dependable resolution. (No pun supposed)

How a lot rapamycin are you crushing up, and into what amount of liquid/cream are you mixing it? The mixtures are given in % of rapamycin, so a 0.045% resolution is just not essentially 45 mg of rapamycin in a given amount of liquid. Understanding the quantity of rapamycin and amount of liquid will let me calculate the % for comparability.

I’ve used about three of the 50 ml OneSkin OS-01 on my face over the previous 6 months most likely. Whereas I do just like the outcomes typically, I really feel it’s means overpriced. They recommend utilizing it twice a day, and with that quantity I may simply see going by way of two 50 ml tubes of it monthly. At $100-120 monthly it provides up. I might be extra apt to purchase if it had been about $80 for 150 ml. It’s unclear if their Physique lotion has the same amount of the peptide. If we will get comparable outcomes with rapamycin pores and skin cream I’d be pleased.

Have you ever been utilizing the Face or Physique cream, and have you ever in contrast the 2?

Please go to the highest of the thread. I consider your whole questions are answered within the subject.

So… what has all of your experiences with rapamycin cream been like, now that you’ve used it for some time?

Do you get phases of dry pores and skin, like with tretinoin? Aside from this, how else would you evaluate it with tretinoin?

I consider it’s known as ethoxyldiglycol: Ethoxydiglycol | Lotioncrafter

What I’m not certain is whether it is any much less pure than that offered by Lab Alley. Lab Alley’s product claims to be USP meals grade purity, and sells for nearly 2x the worth.

Does anybody have any enter on the purity of Lab Alley’s vs Lotioncrafter’s?

Is LC Labs a reliable web site to purchase rapamycin powder? Will powder work or do I want the tablets? The place did you guys get it?

Hello @vas and welcome to the group.

It you may get the LC rapamycin in your pores and skin cream, its advantageous. I’ve a buddy who works in a lab who ordered it for me, however most individuals usually are not ready to do that.

The powder is simple to work with, with not one of the further materials you get within the tablets.

However if you happen to can’t get the powder, simply utilizing the tablets, as recognized on this DIY rapamycin slin cream submit on the high of this thread works advantageous additionally.

I believe I’m going so as to add Astaxanthin to my rapamycin pores and skin cream. Here’s a research that purported to point out advantages from oral and topical software on pores and skin. The ITP research confirmed a 12% improve in median life span from Astaxanthin (males solely).

http://www.actabp.pl/pdf/1_2012/43.pdf

It appears to be a reasonably sturdy purple dye… I believe it will stain your pores and skin.

Why will we dose every day for the pores and skin?, wouldn’t one time per week be extra in line with what we’re saying about typical oral dosing schedules?

I’m conscious of the every day use research that exhibits pores and skin enchancment.

@desertshores I like your method. Are you able to give me the precise breakdown of how a lot water, transcutol and rapamycin that you just use? Additionally, how do you filter it if you happen to don’t have a french press espresso maker (I’m a inexperienced tea man, not a espresso man). There are lots of filtration baggage in the marketplace, I used to be curious if the french press was 5 micron, 10 micron, and so on.

At the moment, I’m utilizing 30 cc transcutol,70cc water, and 10mg Rapacan/sirolimus.
I’m additionally now utilizing a tea strainer as an alternative of the French press as a result of it’s a little bit finer.
We simply wish to filter out the undissolved solids in order to not clog the spritzer bottle. Paper filters I’ve tried are typically very sluggish and retain an excessive amount of of the combination.

Thanks. I’ve ordered the whole lot I want out of your posts and am going to be making an attempt it within the subsequent week or so. Have you ever seen any enhancements with that resolution and, if that’s the case, what are they? Do you might have a hyperlink to the tea strainer you’re utilizing?

Sure. I additionally spray the again of my palms. There’s a particular discount and lightening of liver spots.
I take advantage of a mesh ball opened over a small beaker.

Perhaps I can use my tea strainer I’ve at residence. I’ll give it a shot. Thanks for the precious recommendation.

A random thought. To get rapamycin into the pores and skin and different tissues close to the floor, wouldn’t the niacin flush work? In the event you’re taking rapamycin, it’s in all of your blood and goes the place the blood goes. The niacin flush dilates the small blood vessels within the pores and skin, bringing extra rapamycin to these areas than could be there with out the dilation.

I’ve learn that niacin needs to be taken on an empty abdomen to optimize the flush.

Optimizing the flush is just not an issue. Simply take a bigger dose than you might have been recurrently taking. For anyone not recurrently taking Niacin, don’t begin with greater than 50 or 100. It’ll damage like hell. I critically doubt it’ll get far more Rapa to the pores and skin both.

Not value it.