From my very own restricted expertise, I get the flush with niacin on an empty abdomen however, with the identical dose, not a lot of a flush on a full abdomen. I’ve additionally learn that that’s the case. That’s what I meant by optimizing. I meant the right way to finest elicit the flush phenomenon at any specific dose.
Some folks don’t like the feeling. I do.
You could be proper that the flush gained’t get extra rapamycin to the pores and skin. Possibly the engorged tiny blood vessels don’t ship something to the pores and skin cells. I don’t actually know. However the notion that they do does appear type of intuitive once I look within the mirror and I’m vibrant crimson.
1 Like
No query that vacant abdomen will give larger burn.
My sister in regulation likes the burn, she’s the one one I do know who does. I feel it’s as a result of she’s previous and chilly and it warms her up a bit. Anyway that’s what she says.
Individuals on right here in all probability would know higher than to attempt an enormous dose, however I simply didn’t need that to undergo. It’s an exothermic response within the pores and skin and I’ve examine (although haven’t skilled) precise pores and skin burns from it.
1 Like
Please don’t overlook the photographs earlier than and after.
1 Like
I might, however this can be a DIY thread and I don’t wish to rob you of one in all life’s most transcendent experiences. So, right here in black and white are directions on the right way to make your self crimson throughout. First, you’ll want a bottle of 500 mg niacin drugs, a glass of water and a mirror. Wash down a capsule with the water and interact in some exercise to maintain your thoughts occupied as you eagerly await the flush – minutes can look like hours. When the flush arrives, place your self in entrance of the mirror and dwell within the second.
3 Likes
Hello,
So my powder of rapamycin is just not very tremendous, is that okay if there are pellets? Or does it have to be dissolved? How do I make it extra tremendous/dissolved?
I’m utilizing it topically for angiofibromas on my nostril.
are you crushing it within the bowl like defined within the high posts on this thread? Additionally – then you definately disolve it in transcutol – are you doing that? You may filter out the remnants of the white coating of the tablets (that slows digestion when consumed orally), by utilizing a filter.
1 Like
Is anybody including Metformin to the rapa topical therapy? There are a number of papers displaying that topical use of Metformin is nice for pores and skin. Right here is only one instance https://www.frontiersin.org/articles/10.3389/fmed.2022.813917/full
