My Rapamycin Journey log – Rapamycin Longevity Information

Have been on D3 and K2 for years. Eat handmade cheese + kefir on a regular basis. Want to extend weight bearing workout routines although.

Please share it. I’m very to be taught.

I assume it’d work in case you are poor. However I examined my vit D3 stage and it’s above the low finish of the vary. I dont assume growing it above sure stage will convey any profit for bone density.

My D3 is at all times near the higher stage and typically even increased. However nonetheless my bone density is -1.3 Don’t perceive why. The one clarification that involves thoughts in my case is penalties of kidney transplant.

Yesterday I’ve completed my second DXA scan and the outcome had been fairly much like the preliminary take a look at I’ve completed a month in the past.

Give my low free take a look at and low testosterone as one of many causes for low bone density, I must look extra into the testosterone half.

Hello all once more. I lastly had my second appointment with the endocrinologist yesterday. She is pleased with my hormonal panel and doesn’t think about the present ranges of free T to be too low (which I don’t completely agree). So no therapy on the T aspect for the time being. She did give me a advice to re-check the take a look at ranges in a few months and I requested for a extra full panel, together with SHGB, DHT, DHEA and she or he added others as effectively like Androstenedione, Osteocalcin, β–CTx (Beta-CrossLaps), Estrone (E1) .

As therapy she beneficial

1. Alfacalcidol 0.5 mcg, 1 tb/day
2. 4Bones plus 1 tb/day for the primary 20 days of the month (whole therapy for 1 yr)

On the finish of this era, I’ll retake the DXA scan. I’m not offered on this therapy to be trustworthy and I’ll do some extra analysis earlier than beginning it…

I’m nearer and nearer to my rapa therapy beginning date. I’ll do one other blood panel firstly of subsequent month to have one other baseline.

Fingers crossed!

I acquired my final week blood draw outcomes, and general issues look good, with some exceptions.

Very first thing that I used to be , had been LDL and ApoB, since 3 months have previous from beginning low dose statin of two.5 mg rosuvastatin mixed with 5 mg ezetimibe. The values had been down actually good in comparison with earlier draw:

HDL and trigs are nonetheless across the identical ranges as beforehand

On the flip aspect, I acquired an enormous enhance in ALT and a small one in AST. Not completely satisfied about this, however I learn it might occur for a small proportion of these taking statins. Not completely satisfied in any respect with the outcome and I’m some methods to decrease these enzyme values: Any options are appreciated. I would drop the ezetimib and enhance the rosuvastatin. Unsure which one is at fault right here… or possibly each?

Attention-grabbing is that on third Nov, I acquired ALT examined alongside the hormonal panel (at a unique lab) and it was 39.3 U/L Regular vary of that lab is [5 – 41]. Unsure why 20 days later the worth is a lot worse… Remainder of the hepatic enzymes like GGT, lipaze, amylase, alkaline phosphatase, bilirubin, lactate dehydrogenase (LDH) are regular.

Glucose and insulin are higher, however I believe this is because of in depth weight coaching up to now 6 months.

For the pheno age, I can have an correct studying since I measured all of the params directly

I’m debating if I ought to do a VO2Max as a baseline take a look at as effectively? What do you guys assume?

Given all this information, I imagine I’ll begin with 1mg of rapa subsequent week, probably in Monday.

Thanks for sharing. Don’t be shocked in case your Levine age take a look at markers don’t enhance after taking rapamycin. As I’ve posted earlier than, rapamycin elevated my age on the Levine spreadsheet. Whereas a few markers improved others acquired worse, together with elevated lipids, which isn’t lined on the Levine spreadsheet. Although I don’t count on a 1mg/wk dose of rapa to have any vital impact.

Yeah, I ment I’ll begin with 1 mg on Monday and ramp as much as 6 mg over the following weeks. Sorry for the confusion.

After a dialogue with an MD good friend of mine, I made a decision to drop the ezetimibe and preserve the rosuvastatin as a low dose solely. I’ll redo my blood work in a few months and determine if I’ll enhance it or not.

Going again to the primary matter of this thread, right this moment each me and my spouse, took our first dose of 1mg rapa with a tablespoon of olive oil after our oatmeal breakfast. No vital results to this point, other than a jitteriness and a zit on my eyebrow, but it surely may very well be a coincidence or placebo.

Let the journey start! I’ll preserve you posted.

I believe I might need spoken a contact too early. I simply acquired 2 enormous pores and skin herpes rashes in each of my nostrils. I get all these rashes every now and then, however by no means in each nostrils on the identical time.

Coincidence or not?

My nostril rash is a bit higher, however I’m positively down with a chilly. So is my spouse for that matter. The truth is, half my household is down with a chilly, my sister, mom, nephew, so I assume it could be a coincidence in spite of everything.

Will see if my subsequent dose response can be related or not. Hopefully I’ll get higher by them.

Attention-grabbing. Most probably it’s only a chilly virus, not rapamycin. Unhealthy timing to take the primary dose.

What dose regime did you begin get the rashes and what did you do if you acquired it? Did you decrease the dose, pause consumption or continued taking rapa?

Simply learn up a bit and you’re going to get your reply.

@LaraPo in your huge expertise, do you cease the therapy in case you are down with a chilly? I’m debating if I ought to take my second dose, 2 mg right this moment, since I haven’t recovered from final week chilly but.

Isoconazole works nice on Rapa rashes if utilized rapidly.