Hydroxychloroquine is among the many handful of COVID-19 remedies which can be being studied as potential candidates which may affect the end result within the administration of COVID-19. In line with a actual time meta-analysis of greater than 200 research, early therapy is most profitable.
Hydroxychloroquine, Quercetin and EGCG (EpiGalloCatechin Gallate) are all zinc ionophores. Which means all of them transport zinc into the cells.
We’ll dive deeper into the science for every of them.
Quercetin and COVID-19
Quercetin, Zinc and Vitamin C
There’s proof that vitamin C and quercetin co-administration exerts a synergistic antiviral motion resulting from overlapping antiviral and immuno-modulatory properties and the capability of ascorbate to recycle quercetin, growing its efficacy.
Hydroxychloroquine and COVID-19
Traditionally, hydroxychloroquine was found throughout efforts to synthesize options to quinine as anti-malarials. Is quinine much like hydroxychloroquine? Hydroxychloroquine and quinine are each anti-malarial medication. Nonetheless, hydroxychloroquine isn’t the identical as quinine as hydroxychloroquine is an artificial drug whereas quinine is a naturally occurring compound present in cinchona bark.
Quinine, was first acknowledged as a potent antimalarial agent a whole bunch of years in the past. Since then, the useful results of quinine and its extra superior artificial kinds, chloroquine and hydroxychloroquine, have been more and more acknowledged in a myriad of different illnesses along with malaria.
Hydroxychloroquine, developed within the Nineteen Fifties from chloroquine, an outdated anti-malarial drug, is registered in round 60 international locations underneath commerce names equivalent to Plaquenil, Quensyl and Plaquinol.
Hydroxychloroquine (HCQ) isn’t efficient when used very late with excessive dosages over a protracted interval (RECOVERY/SOLIDARITY), effectiveness improves with earlier utilization and improved dosing. Early therapy persistently exhibits optimistic results. Unfavourable evaluations usually ignore therapy time, usually specializing in a subset of late stage research.
Do you want a prescription for hydroxychloroquine?
Hydroxychloroquine vs Quercetin
Hydroxychloroquine and Quercetin are each zinc ionophores i.e. they transport zinc into the cells.
Nonetheless, quercetin is much less potent than HCQ (hydroxychloroquine) as a zinc transporter, and it doesn’t attain excessive concentrations in lung cells that HCQ does. Quercetin could assist cut back threat of viral sickness in case you are mainly wholesome. However it isn’t potent sufficient to switch HCQ for therapy of COVID after you have signs, and it doesn’t adequately get into lung tissue.
Based mostly on the database on C19Early.com (as of January 2023), quercetin performs higher than hydroxychloroquine for prevention however hydroxychloroquine is superior when it comes to early therapy:
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| Early Remedy: Hydroxychloroquine (62%) vs Quercetin (32%) |
That stated, in case you merely can not get hydroxychloroquine, quercetin is a viable stand-in. Quercetin works greatest when taken with vitamin C and Bromelain, as vitamin C helps activate it and bromelain helps with the absorption. Don’t forget to mix it with zinc.
Though hydroxychloroquine is a comparatively protected drug, it is nonetheless an artificial chemical that may have uncomfortable side effects. Quercetin and Vitamin D, C, Zinc are vitamins that your physique require for optimum well being. Vitamins are safer options particularly in case your threat is low e.g. age beneath 50 and no different persistent sickness.
Talk about along with your physician on the profit vs threat for every therapy. In case you are on a number of drugs, concentrate on supplement-drug interactions which may improve the probabilities of hostile results.
Hydroxychloroquine and quercetin are all a part of the most recent FLCCC I-PREVENT and I-CARE early therapy protocols.
Different Early Remedy Choices
Conclusion
Whereas remedies and dietary supplements are vital elements which may affect the COVID-19 outcomes, do take be aware that elements like pre-existing well being situations, particularly hypertension, diabetes and weight problems would possibly elevate the chance. Take steps to manage hypertension and blood sugar fluctuations with diabetes, as these situations are related to extra extreme illness if contaminated. This will additionally aid you keep a wholesome weight, which is vital as a result of weight problems has been related to an elevated threat of requiring intubation or dying amongst folks hospitalized with COVID-19, notably these underneath 65 years of age. Threat was 60% larger amongst these with extreme weight problems (BMI > 34.9 kg/m2) in comparison with sufferers of regular weight (BMI of 18.5 to 24.9 kg/m2) (R).
Viral infections just like the COVID-19 additionally put added stress in your physique, which might have an effect on your blood stress, coronary heart price, and total coronary heart operate. That may increase your chance of getting a coronary heart assault or stroke. Subsequently, be certain your blood stress is properly managed throughout this pandemic.
- Put on protecting face masks. That is to guard not solely your self however others.
- Considerable proof means that consuming entire in fruits, greens and entire grains—all wealthy in networks of naturally occurring antioxidants and their helper molecules—supplies safety towards free radicals.
- Vaccination
- Getting Sufficient Sleep
- Keep away from Sugar, pink meat and processed meals.
- Do not smoke.
- Take steps to keep away from an infection, equivalent to washing your palms steadily and cooking meats totally.
- Attempt to reduce stress.
- Drink sufficient water to maintain your physique hydrated.
- Keep away from extra alcohol.
- Keep away from crowded areas.
- Common bodily exercise (out of doors actions might not be allowed in international locations with ‘lock-down’).
- Seek the advice of your nearest native healthcare supplier if in case you have any doubt.




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