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Rapamycin and danger of heart problems – rapamycin


Your mindset seems to be that decrease LDL is at all times higher in all contexts. However the epi research exhibits that will not at all times be true. Definitely, as you say, correlational work of that kind has its limits.

(Though the “sick affected person” bias shouldn’t be a significant confounder – that occurs extra if you’re measuring LDL when folks arrive on the hospital; these measurements are years earlier than demise typically. However however, we will’t say for positive – agreed.)

However can’t say for positive is true in each instructions – we will’t say that decrease LDL is useful in all contexts. We lack knowledge.

You say that you simply aren’t saying that “everybody ought to be on a statin.” However after I learn every part you write – aside from that sentence – it looks as if your logic dictates that they need to be. In all probability that is simply as a result of my misunderstanding. However I suppose it might make clear your place when you talked about a couple of examples the place you don’t consider an individual ought to be on a statin.


These ranges look nice. Sadly ApoB doesn’t get lumped in with an ordinary ldl cholesterol check it’s a must to order it individually



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Thanks. That’s what I wished to know. I hoped I might coax the information on ApoB out of the usual ldl cholesterol knowledge, however I suppose not. :frowning:

Easy – I’m not saying everybody ought to be on a statin as a result of there are a number of methods of decreasing LDL/apoB apart from statins. Statins have potential unwanted effects, so as with every intervention there ought to be a value/danger/profit evaluation.

It’s simple to order ApoB when you simply ask subsequent time you get a lipid panel order out of your healthcare supplier. In all probability even higher can be direct measure of LDL particles through NMR Lipoprofile, though it’s costlier too.



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FWIW

NMR LipoProfile® With Lipids and Insulin Resistance Markers
(With Graph)

For LabCorp Take a look at:123638
Within the US $125.00 is quantity billed to insurance coverage within the NYC space.(as of 03/04/2023, spoke to LabCorp CS to get estimate check value)

Evaluate the associated fee, confirm the check code as LabCorp has similar check identify with completely different choices/parameters/measurements.

Evaluate PDF under for testing parameters

NMR LipoProfile Assay Choices Desk.pdf (40.5 KB)

Take a look at value $63.00{was on 03/05/2023 on site] selfpay via Marek.

Store round for the associated fee, as there are various locations providing direct self testing companies.

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