As a matter of precaution earlier than beginning taking rapamycin and acarbose, I had blood work accomplished not too long ago. Every little thing seems to be good, besides is appears my triglycerides are sort of excessive for my age. As a substitute of being < 90 mg/dL, my ranges are round ~110 mg/dL. My different lipid ranges are good, however nonetheless on the upper finish:
I do know taking rapamycin is understood to disregulate lipid homeostasis, so I used to be involved about this. I’ll in all probability construct as much as 3mg/week rapa and do one other blood check in a yr.
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I don’t eat a whole lot of meat most days (as a substitute principally eggs) as a result of I don’t like dealing with meat whereas cooking lol. However not vegetarian.
Take into account afaict they discriminate early 20s ranges of those biomarkers towards grownup biomarkers (I’m in my early 20s), so what could possibly be a wholesome degree later in age may not be wholesome for me proper now if that is smart.
Minimize down in your carbs, in case your glycogen shops are full all of the carbs you eat are transformed to triglycerides. You may additionally add in some hiit (you carry round 2000 kcal price of glycogen in order that’s a whole lot of train ) and/or fasting to empty your glycogen
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That is nice info! I’ve by no means heard that carbs can develop into triglycerides. My triglycerides are just a little excessive however I do have a candy tooth.
Tangentially on that time, I’ve heard that urge for food might be affected by the intestine microbiome—that you just suppose you’re hungry for one thing, nevertheless it’s the intestine micro organism which are hungry and are sending indicators to your mind.
On that idea I’m consuming much more probiotics, principally from meals but in addition in capsule kind now and again. Additionally plenty of fiber, each from meals and powder.
Hopefully this may assist decrease my starvation for carbs, decrease my carbs and possibly triglycerides too.
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By taking acarbose I’m hoping it not directly lowers my triglycerides and different cholestrol markers because it forestall the breakdown of complicated carbs into glucose, however there’s in all probability some organic context I’m lacking right here proper?
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Our our bodies don’t prefer to waste something however as storage of carbs is restricted to round 400g (100g within the liver, the remaining in your muscle) the remaining will get transformed to fat. Amino acids after all too however they’re just about not possible to overeat
For probiotics attempt discovering some actual kefir grains, kefir may be very straightforward to make, very satiating and has the very best probiotic tradition
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Excellent news– my doc mentioned that my ranges are regular and could possibly be dependent off of the meals I ate the day earlier than. Now I’m much less frightened!
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Considering this by… some folks get raised triglycerides whereas on rapamycin. If Rapa tells cells to disregard the nutrient wealthy atmosphere and to clean-up and restore as a substitute of rising and constructing, then individuals who eat usually on rapa days might find yourself with extra energy within the system which are turned to fat. Does this make sense? Appear doubtless? Does this counsel that we must always eat much less on dosage days?
wouldn’t essentially soar to that conclusion. within the ITP each rapa and management teams of mice have been fed the identical means and there was nonetheless the lifespan impact. It may not be the energy that matter, however what you eat as a substitute*
*I might learn a few of these papers which are within the following hyperlink earlier than I state something remotely conclusive. Haven’t learn any of them myself however looks like they provide differing viewpoints as to whether or not rapa will increase cholestrol/triglycerides: https://elicit.org/search?q=does+rapamycin+enhance+fats+shops&token=01GJFRW5KGGCZA4N228A43X4FJ
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Quotation? I do know the alternative. In the event you eat carbs alone, it is not going to get transformed and saved as fats.
