Timing of rapamycin dosing – Rapamycin Longevity Information

I used to be completely unaware that the assay used for A1c was variable. I’ll have to try that.

my good friend complained the opposite day that his Dexocom always undervalues his blood glucose by 5-10% (I’m not certain how related is that, however simply remembered studying your publish).

I did discover a actually good paper on the ketoamine/aldimine points. From reminiscence immunofluourescence will have a tendency to simply get the ketoamine, however ion chromatography will decide up a few of the aldimine as effectively. Aldmine follows glucose (to some extent each methods) by about 2 hours so you will discover that HbA1c additionally metabolises in a pattern if that’s the case.

Once I have a look at my outcomes it’s clear that some labs are selecting up the aldimine as effectively. They are usually within the vary 4.5-5 whereas others are within the vary 4.18-4.6. My spreadsheet clearly tracks which Lab I’m utilizing.

Glucose is difficult to measure that reliably both by fingerstick or CGM. All of them are inclined to range. Dexcoms may be calibrated, nonetheless. I’ve used Dexcom a couple of instances. I’m not diabetic, however I needed to have a baseline as to how my physique handles my regular eating regimen.

different feedback right here I load some comparative outcomes from my Dexcom knowledge:

By the way I are inclined to have the identical breakfast day by day which seems to be like this:
(the dietary supplements range)

A full English half-breakfast.

@John_Hemming I’m so envious! You eat TOAST and beans … and breakfast and have an A1c within the 4’s. Wow.

Thanks for the insights concerning the A1c take a look at variability- this newest take a look at was at a Labcorp web site in SF once I visited there. My earlier annual checks had been at Canadian labs with no hints at the way it was measured.

Will perhaps do one other spherical of utilizing a Dexcom however had hassle isolating the difficulty inflicting the highs as they have a tendency to happen hours after consuming. Undecided it’s an RBC challenge since CGM confirmed comparable scores.

Glad to listen to it might not be the Rapa as a result of I undoubtedly really feel higher on it. Not wildly higher however extra like I felt in my 50’s.

I assumed I might have a look at HbA1c round taking rapamycin (which I’ve completed twice and intend to do once more fairly quickly, however I’ve not but managed to get time in my testing schedule). I’ve these outcomes:
(quoting share then mmol/l with a code for the lab)

24-Aug-22 LM 4.6% 27.1
31-Aug-22 LM 4.7% 27.7
Rapamycin 2mg 4th September
07-Sep-22 LM 4.5 25.9
12-Sep-22 MPS 4.18 22
26-Oct-22 LM 28.2

06-Jan-23 NWP 4.9 30
Rapamycin 2mg tenth Jan
11-Jan-23 LM 30.5
19-Jan-23 NWP 4.7 28
25-Jan-23 NWP 4.8 29
31-Jan-23 NWP 4.9 30

I believe MPS don’t take a look at for aldimine and that’s the reason HbA1c was 4.18 quite than Rapamycin. In any other case I believe the varations are noise.

The Dexcom claims to not require calibration however that’s as a result of they settle for a +- 20 on the glucose measurement since it’s FDA accepted for remedy of kind 1 diabetes and the numbers are often fairly excessive >120. When it isn’t calibrated the numbers may be off by 20+ factors.
For these of us who use it to optimize glucose ranges it must be calibrated virtually every day. Once I’ve calibrated it every day (utilizing two separate glucometers) the numbers are typically fairly correct.

I do discover the Dexcom G7 higher than the G6. I have a tendency to purchase three periods at a time, however I plan once I use a session to overlap with different checks I’m doing. It was fascinating, for instance, to see a blood sugar drop on Dexcom while I used to be sleeping and a time launch concoction of my very own utilizing melatonin kicked in.

(I make up time launch variations by utilizing a number of delayed launch capsules inside one another – this takes a little bit of time, nevertheless it permits helpful delays earlier than issues kick in.)

Grabovac

Which glucometers{GM] do you employ?

Do you test the GM with references options earlier than really blood take a look at?

I envy you! Your breakfast seems to be wonderful. Please publish photos of your lunch and dinner!