domingo, agosto 23, 2026
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Weight Setpoint? – Rapamycin Longevity Information


I used to be a bit shocked that regardless of being off the rail when it got here to weight-reduction plan over the vacations, the burden I had misplaced earlier than Christmas didn’t come again on. I’d misplaced about 8lbs by way of food regimen and train, and in comparable circumstances, my physique would have usually regained a lot of it again throughout the holidays and the extreme energy that comes with it. Preventing with my weight has been a relentless battle and preserving weight off takes lots of diligence for me.

I did see this 2014 pubmed article on rapamycin and weight setpoints. I ponder if others have seen this phenomenon as effectively?




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Sure, you might be proper and plenty of articles tout that rapamycin can reset your weight level.

I went from 196 kilos… after three months on rapamycin… misplaced weight weekly and I reset to 181. That was 2 years in the past…

I eat continuously … every part and if it goes up on a Vacation buffet 3 day binge to say 187 kilos…in just a few days it’s again to 181.

I weigh on a regular basis butt bare… earlier than leaping within the bathe.

My weight set level is now 181 kilos… I prefer it.



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I want that was my expertise. I’ve gained about 8 kilos since I began rapa this summer time. I take 6mg each Saturday morning on an empty abdomen. Weighed in at 189 final morning however common round 185. Would a better dose assist?



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Possibly take your dose with a little bit of GFJ? Kick it up?

I used to be truly pondering the upper rapamycin dosing would clear an increasing number of fats and different crap out of me … it did.

Fairly shredded now. Went from a 34 inch waist to 31 inch now.

Peter Attia and Matt Kaeberlein each do 8 mg to 10 weekly.

Price a shot.

Humorous how our phenotypes reply to Rapamycin. It responds to your modified points. I’ve at all times had a small body… it has adjusted again to my early self… simply now in higher form.

Me 20 years in the past… fairly skinny.

Me 6 years in the past.

Me now. So possibly takes you again extra to earlier self.



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No, that’s what 2x TRT dosing does…

No I might advocate towards taking extra.

What model are you utilizing atm?

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